Natural ingredients and probiotics for lowering cholesterol and saturated fat in dairy products: an updated review
Main Article Content
Keywords
dairy products, natural ingredients, probiotics, cholesterol-lowering, saturated fat reduction, functional foods
Abstract
Dairy products play a crucial role in ensuring healthy lives and promoting the well-being of people. However, they normally contain high levels of saturated fat and cholesterol which are related to the risk of noncommunicable diseases and other health issues. Our review focuses on the effectiveness of added natural ingredients and probiotics in dairy products for replacing or lowering cholesterol and saturated fat. This narrative review was conceptualized to describe: (i) natural ingredients for cholesterol and saturated fat substitution, and (ii) probiotics for lowering both cholesterol and saturated fat. Promising techniques for cholesterol and saturated fat replacement by healthy plant oils, carbohydrate, and protein co-products and their effect on product qualities are discussed. In addition, various probiotics inoculated in dairy products exhibiting effect on saturated fat and cholesterol are also addressed.
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Ahmed, R.M., Elsanhoty, R.M., Al-Saman, M.A.A. and Ramadan, M.F., 2017. Hypocholesterolaemic effect of probiotic yogurt enriched with barley β-glucan in rats fed on a high-cholesterol diet. Mediterranean Journal of Nutrition and Metabolism 10(1): 1–12. 10.3233/MNM-16114
Aini, N., Sumarmono, J., Sustriawan, B., Prihananto, V. and Priscillia, E., 2020. The quality of corn milk-based cheese analogue made with virgin coconut oil as a fat substitute and with various emulsifiers. IOP Conference Series: Earth and Environmental Science 443(1): 12039. 10.1088/1755-1315/443/1/012039
Akbari, M., Eskandari, M.H. and Davoudi, Z., 2019. Application and functions of fat replacers in low-fat ice cream: a review. Trends in Food Science and Technology 86: 34–40. 10.1016/j.tifs.2019.02.036
Alasalvar, H., Kocer Alasalvar, G., and Yıldırım, Z., 2022. Effect of partial fat replacement by hazelnut oil microcapsules in beef burger formulations on physicochemical properties, fatty acid composition, and sensory attributes. Journal of Food Processing and Preservation 46(5): e16644.
Albano, C., Morandi, S., Silvetti, T., Casiraghi, M.C., Manini, F. and Brasca, M., 2018. Lactic acid bacteria with cholesterol-lowering properties for dairy applications: in vitro and in situ activity. Journal of Dairy Science 101(12): 10807–10818. 10.3168/jds.2018-15096
Almada-Érix, C.N., Almada, C.N., Cabral, L., Barros de Medeiros, V.P., Roquetto, A.R., Santos-Junior, V.A., et al. 2021. Orange juice and yogurt carrying probiotic Bacillus coagulans GBI-30 6086: impact of intake on Wistar male rats health parameters and gut bacterial diversity. Frontiers in Microbiology 12: 623951. 10.3389/fmicb.2021.623951
Alston, M.C., Redman, L.M. and Sones, J.L., 2022. An overview of obesity, cholesterol, and systemic inflammation in Preeclampsia. Nutrients 14(10): 2087.
Álvarez-Castillo, E., Felix, M., Bengoechea, C. and Guerrero, A., 2021. Proteins from agri-food industrial biowastes or co-products and their applications as green materials. Foods 10(5): 981. 10.3390/foods10050981
Angelin, J. and Kavitha, M., 2020. Exopolysaccharides from probiotic bacteria and their health potential. International Journal of Biological Macromolecules 162: 853–865. 10.1016/j.ijbiomac.2020.06.190
Ansari, F., Alian Samakkhah, S., Bahadori, A., Jafari, S.M., Ziaee, M., Khodayari, M.T., et al. 2021. Health-promoting properties of Saccharomyces cerevisiae var. boulardii as a probiotic; characteristics, isolation, and applications in dairy products. Critical Reviews in Food Science and Nutrition 63(4): 457–485. 10.1080/10408398.2021.1949577
Anvari, M. and Joyner (Melito), H.S., 2019. Concentrated emulsions as novel fat replacers in reduced-fat and low-fat Cheddar cheeses. Part 2. Large amplitude oscillatory shear behavior. International Dairy Journal 91: 137–146. 10.1016/j.idairyj.2018.08.018
Aslam, H.K.W., Saeed, M., Shakeel, A., Pasha, İ., Shabbir, M.A. and Raza, M.S., 2015. Extraction of Inulin from Cichorium intybus and its application as fat replacer in yoghurt. Journal of Applied Biological Sciences 9(3): 86–94. Retrieved from https://jabsonline.org/index.php/jabs/article/view/464
Aydinol, P. and Ozcan, T., 2018. Production of reduced-fat Labneh cheese with inulin and β-glucan fibre-based fat replacer. International Journal of Dairy Technology 71(2): 362–371. 10.1111/1471-0307.12456
Aziz, N.S., Sofian-Seng, N.S., Yusop, S.M., Kasim, K.F. and Razali, N.S.M., 2018. Functionality of okra gum as a novel carbohydrate-based fat replacer in ice cream. Food Science and Technology Research 24(3): 519–530. 10.3136/fstr.24.519
Babu, A.S., Parimalavalli, R. and Jagan Mohan, R., 2018. Effect of modified starch from sweet potato as a fat replacer on the quality of reduced fat ice creams. Journal of Food Measurement and Characterization 12(4): 2426–2434. 10.1007/s11694-018-9859-4
Bagheri, F., Radi, M. and Amiri, S., 2018. Evaluating the function of cross-linked rice starch as a fat replacer in low fat cream. International Journal of Dairy Technology 71(4): 981–991. 10.1111/1471-0307.12510
Basiony, M. and Hassabo, R., 2022. Composition and quality of low-fat Halloumi cheese made using modified starch as a fat replacer. Starch (Stärke) 74(3–4): 2100211. 10.1002/star.202100211
Bellinazo, P.L., Vitola, H.R.S., Cruxen, C.E. dos S., Braun, C.L.K., Hackbart, H.C. dos S., da Silva, W.P., et al. 2019. Probiotic butter: viability of Lactobacillus casei strains and bixin antioxidant effect (Bixa orellana L.). Journal of Food Processing and Preservation 43(9): e14088. 10.1111/jfpp.14088
Bemer, H.L., Limbaugh, M., Cramer, E.D., Harper, W.J. and Maleky, F., 2016. Vegetable organogels incorporation in cream cheese products. Food Research International 85: 67–75. 10.1016/j.foodres.2016.04.016
Bezerra, T.K.A., de Oliveira Arcanjo, N.M., Garcia, E.F., Gomes, A.M.P., de Cássia Ramos do Egypto Queiroga, R., de Souza, E.L., et al. 2017. Effect of supplementation with probiotic lactic acid bacteria, separately or combined, on acid and sugar production in goat ‘Coalho’ cheese. LWT–Food science and Technology 75: 710–718. 10.1016/j.lwt.2016.10.023
Canton, H., 2021. Food and Agriculture Organization of the United Nations—FAO. In: The Europa directory of international organizations 2021. Routledge, Abingdon-on-Thames, Oxfordshire, UK, pp. 297–305.
Cardoso, L.G., Junior, I.J.B., da Silva, R.V., Mossmann, J., Reinehr, C.O., Brião, V.B., et al. 2020. Processed cheese with inulin and microencapsulated chia oil (Salvia hispanica). Food Bioscience 37: 100731. 10.1016/j.fbio.2020.100731
Castellone, V., Bancalari, E., Rubert, J., Gatti, M., Neviani, E. and Bottari, B., 2021. Eating fermented: health benefits of lab-fermented foods. Foods 10: 2639. 10.3390/foods10112639
Chalupa-Krebzdak, S., Long, C.J. and Bohrer, B.M., 2018. Nutrient density and nutritional value of milk and plant-based milk alternatives. International Dairy Journal 87: 84–92. 10.1016/j.idairyj.2018.07.018
Chen, Y., She, Y., Zhang, R., Wang, J., Zhang, X. and Gou, X., 2020. Use of starch-based fat replacers in foods as a strategy to reduce dietary intake of fat and risk of metabolic diseases. Food Science & Nutrition 8: 16–22. 10.1002/fsn3.1303
Cho, W.Y., Hong, G.E., Lee, H.J., Yeon, S.J., Paik, H.D., Hosaka, Y.Z., et al. 2020. Effect of yogurt fermented by Lactobacillus fermentum Tsi and L. Fermentum S2 derived from a Mongolian traditional dairy product on rats with high-fat-diet-induced obesity. Foods 9: 594. 10.3390/foods9050594
Dai, S., Jiang, F., Shah, N.P. and Corke, H., 2019. Functional and pizza bake properties of Mozzarella cheese made with Konjac glucomannan as a fat replacer. Food Hydrocolloids 92: 125–134. 10.1016/j.foodhyd.2019.01.045
Das, K., Choudhary, R., and Thompson-Witrick, K. A., 2019. Effects of new technology on the current manufacturing process of yogurt-to increase the overall marketability of yogurt. LWT–Food science and Technology 108: 69–80. 10.1016/j.lwt.2019.03.058
Decimo, M., Brasca, M., Ordóñez, J.A. and Cabeza, M.C., 2017. Fatty acids released from cream by psychrotrophs isolated from bovine raw milk. International Journal of Dairy Technology 70: 339–344. 10.1111/1471-0307.12347
Derewiaka, D., Stepnowska, N., Bryś, J., Ziarno, M., Ciecierska, M. and Kowalska, J., 2019. Chia seed oil as an additive to yogurt. Grasas y Aceites 70(2): e302. 10.3989/gya.0705182
Deus, A.F., Vileigas, D.F., Silva, D.C.T., Tomasi, L.C., Campos, D.H.S., Okoshi, K., et al. 2019. Cardiac function and intracellular Ca2+ handling proteins are not impaired by high-saturated-fat diet-induced obesity. Brazilian Journal of Medical and Biological Research 52: e8085. 10.1590/1414-431X20198085
Diamantino, V.R., Costa, M.S., Taboga, S.R., Vilamaior, P.S., Franco, C.M., and Penna, A.L.B., 2019. Starch as a potential fat replacer for application in cheese: behaviour of different starches in casein/starch mixtures and in the casein matrix. International Dairy Journal 89: 129–138. 10.1016/j.idairyj.2018.08.015
Ding, X., Zhang, W., Li, S. and Yang, H., 2019. The role of cholesterol metabolism in cancer. American Journal of Cancer Research 9(2): 219. PMCID: PMC6405981
El-Assar, M.A., Abou-Dawood, S.A., Sakr, S.S. and Younis, N.M., 2019. Low-fat processed cheese spread with added inulin: its physicochemical, rheological and sensory characteristics. International Journal of Dairy Science 14: 12–20. 10.3923/ijds.2019.12.20
Fadl, M.G. and Kamel, Z., 2022. Cholesterol-lowering effects and safety assessment of Lactobacillus spp. in vivo and in vitro testing for human use as probiotic from the dairy product in Egypt. Journal of Genetic Engineering and Biotechnology 20(1): 1–11. 10.1186/s43141-022-00423-3
Fan, J., Liu, Y., Yin, S., Chen, N., Bai, X., Ke, Q., et al. 2019. Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation. Nutrition & Metabolism 16(1): 1–9. 10.1186/s12986-019-0334-y. eCollection 2019.
Farias, D. de P., de Araújo, F.F., Neri-Numa, I.A. and Pastore, G.M., 2019. Prebiotics: trends in food, health and technological applications. Trends in Food Science and Technology 93: 23–35. 10.1016/j.tifs.2019.09.004
Ferguson, J.J.A., Stojanovski, E., MacDonald-Wicks, L. and Garg, M.L., 2016. Fat type in phytosterol products influence their cholesterol-lowering potential: a systematic review and meta-analysis of RCTs. Progress in Lipid Research 64: 16–29. 10.1016/j.plipres.2016.08.002
Fidalgo Rodríguez, J.L., Dynarowicz-Latka, P. and Miñones Conde, J., 2020. How unsaturated fatty acids and plant stanols affect sterols plasma level and cellular membranes? Review on model studies involving the Langmuir monolayer technique. Chemistry and Physics of Lipids 232: 104968. 10.1016/j.chemphyslip.2020.104968
Frappier, M., Auclair, J., Bouasker, S., Gunaratnam, S., Diarra, C. and Millette, M., 2022. Screening and characterization of some Lactobacillaceae for detection of cholesterol-lowering activities. Probiotics and Antimicrobial Proteins 14(5): 873–883. 10.1007/s12602-022-09959-9
Garcia-Estevez, L. and Moreno-Bueno, G., 2019. Updating the role of obesity and cholesterol in breast cancer. Breast Cancer Research 21(1): 1–8. 10.1186/s13058-019-1124-1
Gebreyowhans, S., Lu, J., Zhang, S., Pang, X. and Lv, J., 2019. Dietary enrichment of milk and dairy products with n-3 fatty acids: a review. International Dairy Journal 97: 158–166. 10.1016/j.idairyj.2019.05.011
Genovese, A., Balivo, A., Salvati, A. and Sacchi, R., 2022. Functional ice cream health benefits and sensory implications. Food Research International 161: 111858. 10.1016/j.foodres.2022.111858
Gibson, G.R., Hutkins, R., Sanders, M.E., Prescott, S.L., Reimer, R.A., Salminen, S.J., et al. 2017. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nature Reviews Gastroenterology and Hepatology 14(8): 491–502. 10.1038/nrgastro.2017.75
Givens, D.I., 2017. Saturated fats, dairy foods and health: a curious paradox? Nutrition Bulletin 42(3): 274–282. 10.1111/nbu.12283
Godoi, F.C., Ningtyas, D.W., Geoffroy, Z. and Prakash, S., 2021. Protein-based hydrocolloids: effect on the particle size distribution, tribo-rheological behaviour and mouthfeel characteristics of low-fat chocolate flavoured milk. Food Hydrocolloids 115: 106628. 10.1016/j.foodhyd.2021.106628
Gómez-Cortés, P., Juárez, M. and de la Fuente, M.A., 2018. Milk fatty acids and potential health benefits: an updated vision. Trends in Food Science and Technology 81: 1–9. 10.1016/j.tifs.2018.08.014
Granholm, A.C., Bimonte-Nelson, H.A., Moore, A.B., Nelson, M.E., Freeman, L.R. and Sambamurti, K., 2008. Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat. Journal of Alzheimer’s Disease 14(2): 133–145. 10.3233/jad-2008-14202
Guven, M., Yasar, K., Karaca, O.B. and Hayaloglu, A.A., 2005. The effect of inulin as a fat replacer on the quality of set-type low-fat yogurt manufacture. International Journal of Dairy Technology 58(3): 180–184. 10.1111/j.1471-0307.2005.00210.x
Hackam, D.G. and Hegele, R.A., 2019. Cholesterol lowering and prevention of stroke: an overview. Stroke 50(2): 537–541. 10.1161/STROKEAHA.118.023167
He, W.-S., Zhu, H. and Chen, Z.Y. 2018. Plant sterols: chemical and enzymatic structural modifications and effects on their cholesterol-lowering activity. Journal of Agricultural and Food Chemistry 66(12): 3047–3062. 10.1021/acs.jafc.8b00059
Holscher, H.D., 2017. Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes 8(2): 172–184. 10.1080/19490976.2017.1290756
Hossain, M.K., Keidel, J., Hensel, O. and Diakité, M. 2020. The impact of extruded microparticulated whey proteins in reduced-fat, plain-type stirred yogurt: characterization of physicochemical and sensory properties. LWT–Food Science and Technology 134: 109976. 10.1016/j.lwt.2020.109976
Hu, G.G., Liu, J., Wang, Y.H., Yang, Z.N. and Shao, H.B., 2022. Applications of plant protein in the dairy industry. Foods 11(8): 1067. 10.3390/foods11081067
Hurtado-Romero, A., Del Toro-Barbosa, M., Garcia-Amezquita, L.E. and García-Cayuela, T. 2020. Innovative technologies for the production of food ingredients with prebiotic potential: modifications, applications, and validation methods. Trends in Food Science and Technology 104: 117–131. 10.1016/j.tifs.2020.08.007
Ibrahim, F.N., Ismail-Fitry, M.R., Yusoff, M.M. and Shukri, R., 2018. Effects of fish collagen hydrolysate (FCH) as fat replacer in the production of buffalo patties. Journal of Advanced Research in Applied Sciences and Engineering Technology 11(1): 108–117. Retrieved from https://akademiabaru.com/submit/index.php/araset/article/view/1964
Ipsen, R., 2017. Microparticulated whey proteins for improving dairy product texture. International Dairy Journal 67: 73–79. 10.1016/j.idairyj.2016.08.009
Ishimwe, N., Daliri, E.B., Lee, B.H., Fang, F. and Du, G., 2015. The perspective on cholesterol-lowering mechanisms of probiotics. Molecular Nutrition and Food Research 59(1): 94–105. 10.1002/mnfr.201400548
Jardines, A.P., Arjona-Roman, J.L., Severiano-Perez, P., Totosaus-S, A., Fiszman, S. and Escalona-Buendía, H.B., 2020. Agave fructans as fat and sugar replacers in ice cream: sensory, thermal and texture properties. Food Hydrocolloids 108: 106032. 10.1016/j.foodhyd.2020.106032
Jitpakdee, J., Kantachote, D., Kanzaki, H. and Nitoda, T., 2021. Selected probiotic lactic acid bacteria isolated from fermented foods for functional milk production: lower cholesterol with more beneficial compounds. LWT–Food Science and Technology 135: 110061. 10.1016/j.lwt.2020.110061
Jurić, S., Jurić, M., Siddique, M.A.B. and Fathi, M., 2022. Vegetable oils rich in polyunsaturated fatty acids: nanoencapsulation methods and stability enhancement. Food Reviews International 38(1): 32–69. 10.1080/87559129.2020.1717524
Kale, R.V., Sontakke, M.D., Raut G.S. and Chavan, V.R., 2020. Use of enzyme modified sweet potato starch in formulation of ice cream. International Journal of Chemical Studies 8(4): 3002–3008. 10.22271/chemi.2020.v8.i4aj.10110
Kalmijn, S., Van Boxtel, M.P.J., Ocke, M., Verschuren, W.M.M., Kromhout, D. and Launer, L.J., 2004. Dietary intake of fatty acids and fish in relation to cognitive performance at middle age. Neurology 62(2): 275–280. 10.1212/01.wnl.0000103860.75218.a5
Karimi, R., Azizi, M.H., Ghasemlou, M. and Vaziri, M., 2015. Application of inulin in cheese as prebiotic, fat replacer and texturizer: a review. Carbohydrate Polymers 119: 85–100. 10.1016/j.carbpol.2014.11.029
Kaur, R., Panwar, D. and Panesar, P.S., 2020. Biotechnological approach for valorization of whey for value-added products. In: Food industry wastes: Academic Press, pp. 275–302. 10.1016/b978-0-12-817121-9.00013-9
Kawee-ai, A., Ritthibut, N., Manassa, A., Moukamnerd, C., Laokuldilok, T., Surawang, S., et al. 2018. Optimization of simultaneously enzymatic fructo-and inulo-oligosaccharide production using co-substrates of sucrose and inulin from Jerusalem artichoke. Preparative Biochemistry and Biotechnology 48(2): 194–201. 10.1080/10826068.2018.1425708
Kew, B., Holmes, M., Stieger, M. and Sarkar, A., 2020. Review on fat replacement using protein-based microparticulated powders or microgels: a textural perspective. Trends in Food Science and Technology 106: 457–468. 10.1016/j.tifs.2020.10.032
Khalil, N.A., Eltahan, N.R., Elaktash, H.M., Aly, S. and Sarbini, S.R., 2021. Prospective evaluation of probiotic and prebiotic supplementation on diabetic health associated with gut microbiota. Food Bioscience 42: 101149. 10.1016/j.fbio.2021.101149
Kim, S.Y., Hyeonbin, O., Lee, P. and Kim, Y., 2020. The quality characteristics, antioxidant activity, and sensory evaluation of reduced-fat yogurt and nonfat yogurt supplemented with basil seed gum as a fat substitute. Journal of Dairy Science 103: 1324–1336. 10.3168/jds.2019-17117
Kim, Y., Yoon, S., Shin, H., Jo, M., Lee, S. and Kim, S.H., 2021. Isolation of the cholesterol-assimilating strain Pediococcus acidilactici LRCC5307 and production of low-cholesterol butter. Food Science of Animal Resources 41(2): 300–311. 10.5851/kosfa.2020.e101
Kliem, K.E., Humphries, D.J., Markey, O., Vasilopoulou, D., Fagan, C.C., Grandison, A.S., et al. 2019. Food chain approach to lowering the saturated fat of milk and dairy products. International Journal of Dairy Technology 72: 100–109.
Kokabi, S., Soltani, M., Dabirian, S., Kokabian, A., Daraei Garmakhany, A., et al. 2021. Incorporation of omega-3 fatty acid-rich grape seed oil in yoghurt: response surface optimization of physicochemical, textural, and sensory attributes during refrigerated storage. Food Science & Nutrition 9(1): 331–344. 10.1002/fsn3.1998
Korcz, E., Kerényi, Z. and Varga, L., 2018. Dietary fibers, prebiotics, and exopolysaccharides produced by lactic acid bacteria: potential health benefits with special regard to cholesterol-lowering effects. Food & Function 9: 3057–3068. 10.1039/c8fo00118a
Kouhi, F., Mirzaei, H., Nami, Y., Khandaghi, J. and Javadi, A., 2022. Potential probiotic and safety characterisation of enterococcus bacteria isolated from indigenous fermented motal cheese. International Dairy Journal 126: 105247. 10.1016/j.idairyj.2021.105247
Kozłowska, M., Gruczyńska, E., Ścibisz, I. and Rudzińska, M., 2016. Fatty acids and sterols composition, and antioxidant activity of oils extracted from plant seeds. Food Chemistry 213: 450–456. 10.1016/j.foodchem.2016.06.102
Kris-Etherton, P.M. and Krauss, R.M., 2020. Public health guidelines should recommend reducing saturated fat consumption as much as possible: YES. American Journal of Clinical Nutrition 112(1): 13–18. 10.1093/ajcn/nqaa110
Laiho, S., Williams, R.P.W., Poelman, A., Appelqvist, I. and Logan, A., 2017. Effect of whey protein phase volume on the tribology, rheology and sensory properties of fat-free stirred yogurts. Food Hydrocolloids 67: 166–177. 10.1016/j.foodhyd.2017.01.017
Leong, T.S.H., Ong, L., Gamlath, C.J., Gras, S.L., Ashok kumar, M. and Martin, G.J.O., 2020. Formation of cheddar cheese analogues using canola oil and ultrasonication—a comparison between single and double emulsion systems. International Dairy Journal 105: 104683. 10.1016/j.idairyj.2020.104683
Li, H., Liu, T., Zou, X., Yang, C., Li, H., Cui, W., et al. 2021. Utilization of thermal-denatured whey protein isolate-milk fat emulsion gel microparticles as stabilizers and fat replacers in low-fat yogurt. LWT–Food Science and Technology 150: 112045. 10.1016/j.lwt.2021.112045
Li, J.M. and Nie, S.P., 2016. The functional and nutritional aspects of hydrocolloids in foods. Food Hydrocolloids 53: 46–61. 10.1016/j.foodhyd.2015.01.035
Liu, R., Wang, L., Liu, Y., Wu, T. and Zhang, M., 2018. Fabricating soy protein hydrolysate/xanthan gum as fat replacer in ice cream by combined enzymatic and heat-shearing treatment. Food Hydrocolloids 81: 39–47. 10.1016/j.foodhyd.2018.01.031
Lobato-Calleros, C., Recillas-Mota, M.T., Espinosa-Solares, T., Alvarez-Ramirez, J. and Vernon-Carter, E.J., 2009. Microstructural and rheological properties of low-fat stirred yoghurts made with skim milk and multiple emulsions. Journal of Texture Studies 40(6): 657–675.
Lordan, R., Tsoupras, A., Mitra, B. and Zabetakis, I., 2018. Dairy fats and cardiovascular disease: do we really need to be concerned? Foods 7: 29. 10.3390/foods7030029
MacDonald, C.J., Madkia, A.L., Mounier-Vehier, C., Severi, G. and Boutron-Ruault, M.C., 2022. Associations between saturated fat intake and other dietary macronutrients and incident hypertension in a prospective study of French women. European Journal of Nutrition 62: 1207–1215. 10.1007/s00394-022-03053-0
Mahmmodi, P., Khoshkhoo, Z., Basti, A.A., Shotorbani, P.M. and Khanjari, A., 2021. Effect of Bunium persicum essential oil, NaCl, bile salts, and their combinations on the viability of Lactobacillus acidophilus in probiotic yogurt. Quality Assurance and Safety of Crops and Foods 13(1): 37–48. 10.15586/qas.v13i1.858
Mantzouridou, F.T., Naziri, E., Kyriakidou, A., Paraskevopoulou, A., Tsimidou, M.Z. and Kiosseoglou, V., 2019. Oil bodies from dry maize germ as an effective replacer of cow milk fat globules in yogurt-like product formulation. LWT–Food Science and Technology 105: 48–56. 10.1016/j.lwt.2019.01.068
Mayengbam, S.S., Singh, A., Pillai, A.D. and Bhat, M.K., 2021. Influence of cholesterol on cancer progression and therapy. Translational Oncology 14(6): 101043. 10.1016/j.tranon.2021.101043.
Mensi, A. and Udenigwe, C.C., 2021. Emerging and practical food innovations for achieving the Sustainable Development Goals (SDG) target 2.2. Trends in Food Science and Technology 111: 783–789. 10.1016/j.tifs.2021.01.079
Minj, J., Chandra, P., Paul, C. and Sharma, R.K., 2021. Bio-functional properties of probiotic Lactobacillus: current applications and research perspectives. Critical Reviews in Food Science and Nutrition 61: 2207–2224. 10.1080/10408398.2020.1774496
Modzelewska-Kapituła, M. and Kłębukowska, L., 2009. Investigation of the potential for using inulin HPX as a fat replacer in yoghurt production. International Journal of Dairy Technology 62: 209–214. 10.1111/j.1471-0307.2009.00481.x
Mofid, V., Izadi, A., Mojtahedi, S.Y. and Khedmat, L., 2020. Therapeutic and nutritional effects of synbiotic yogurts in children and adults: a clinical review. Probiotics and Antimicrobial Proteins 12(3): 851–859. 10.1007/s12602-019-09594-x
Moriano, M.E. and Alamprese, C., 2017. Organogels as novel ingredients for low saturated fat ice creams. LWT–Food science and Technology 86: 371–376.
Munekata, Paulo ES, Rubén Domínguez, Sravanthi Budaraju, Elena Roselló-Soto, Francisco, J., Barba, et al. 2020. Effect of innovative food processing technologies on the physicochemical and nutritional properties and quality of non-dairy plant-based beverages. Foods 9(3): 288. 10.3390/foods9030288
Nourmohammadi, N., Austin, L. and Chen, D., 2023. Protein-based fat replacers: a focus on fabrication methods and fat-mimic mechanisms. Foods 12(5): 957. 10.1080/87559129.2019.1701007
Ostadzadeh, M., Habibi Najafi, M.B. and Ehsani, M.R., 2022. Lactic acid bacteria isolated from traditional Iranian butter with probiotic and cholesterol-lowering properties: in vitro and in situ activity. Food Science & Nutrition 11: 350–363. 10.1002/fsn3.3066
Pandule, V.S., Sharma, M., Devaraja, H.C. and Surendra Nath, B., 2021. Omega-3 fatty acid-fortified butter: preparation and characterisation of textural, sensory, thermal, and physico-chemical properties. International Journal of Dairy Technology 74:181–191. 10.1111/1471-0307.12750
Papademas, P. and Kotsaki, P., 2020. Technological utilization of whey towards sustainable exploitation. Advances in Dairy Research 7: 1–10. 10.35248/2329-888x.7.4.231
Parvez, S., Malik, K.A., Ah Kang, S. and Kim, H.Y., 2006. Probiotics and their fermented food products are beneficial for health. Journal of Applied Microbiology 100: 1171–1185. 10.1111/j.1365-2672.2006.02963.x.
Patel, A., Desai, S.S., Mane, V.K., Enman, J., Rova, U., Christakopoulos, P., et al. 2022. Futuristic food fortification with a balanced ratio of dietary ω-3/ω-6 omega fatty acids for the prevention of lifestyle diseases. Trends in Food Science and Technology 120: 140–153. 10.1016/j.tifs.2022.01.006
Patel, A.R., Nicholson, R.A. and Marangoni, A.G., 2020. Applications of fat mimetics for the replacement of saturated and hydrogenated fat in food products. Current Opinion in Food Science 33: 61–68. 10.1016/j.cofs.2019.12.008
Pehlivanoğlu, H., Demirci, M., Toker, O.S., Konar, N., Karasu, S. and Sagdic, O., 2018. Oleogels, a promising structured oil for decreasing saturated fatty acid concentrations: production and food-based applications. Critical Reviews in Food Science and Nutrition 58(8): 1330–1341. 10.1080/10408398.2016.1256866
Peng, X. and Yao, Y., 2017. Carbohydrates as fat replacers. Annual Review of Food Science and Technology 8: 331–351. 10.1146/annurev-food-030216-030034
Pirsa, S. and Hafezi, K., 2023. Hydrocolloids: Structure, preparation method, and application in food industry. Food Chemistry 399: 133967. 10.1016/j.foodchem.2022.133967
Pourrajab, B., Fatahi, S., Dehnad, A., Kord Varkaneh, H. and Shidfar, F., 2020. The impact of probiotic yogurt consumption on lipid profiles in subjects with mild to moderate hypercholesterolemia: a systematic review and meta-analysis of randomized controlled trials. Nutrition, Metabolism and Cardiovascular Diseases 30(1): 11–22. 10.1016/j.numecd.2019.10.001
Ramel, P.R. and Marangoni, A.G., 2018. Processed cheese as a polymer matrix composite: a particle toolkit for the replacement of milk fat with canola oil in processed cheese. Food Research International 107: 110–118. 10.1016/j.foodres.2018.02.019
Ribeiro, A. de S., da SILVA, M.N., Tagliapietra, B.L., Brum Júnior, B. de S., Ugalde, M.L. and Richards, N.S.P.D.S., 2019. Development of symbiotic yogurt and biological evaluation (New Zealand white rabbits) of its functional properties. Food Science & Technology 39: 418–425. 10.1590/fst.20618
Ribes, S., Peña, N., Talens, P. and Barat, J.M., 2021. Chia (Salvia hispanica L.) seed mucilage as a fat replacer in yogurts: effect on their nutritional, technological, and sensory properties. Journal of Dairy Research 140: 2822–2833. 10.3168/jds.2020-19240
Rolim, F.R.L., Freitas Neto, O.C., Oliveira, M.E.G., Oliveira, C.J.B. and Queiroga, R.C.R.E., 2020. Cheeses as food matrixes for probiotics: in vitro and in vivo tests. Trends in Food Science and Technology 100: 138–154. 10.1016/j.tifs.2020.04.008
Romanić, R.S., Lužaić, T.Z. and Radić, B.Đ., 2021. Enriched sunflower oil with omega 3 fatty acids from flaxseed oil: prediction of the nutritive characteristics. LWT–Food Science and Technology 150: 112064. 10.1016/j.lwt.2021.112064
Romero-Luna, H.E., Peredo-Lovillo, A.G. and Jiménez-Fernández, M., 2021. Probiotic and potentially probiotic bacteria with hypocholesterolemic properties. Food Reviews International 1–19. 10.1080/87559129.2021.1926481
Samakradhamrongthai, R.S., Jannu, T., Supawan, T., Khawsud, A., Aumpa, P. and Renaldi, G., 2021. Inulin application on the optimization of reduced-fat ice cream using response surface methodology. Food Hydrocolloids 119: 106873. 10.1016/j.foodhyd.2021.106873
Santos, P.H.D.S. and Lannes, S.C.D.S., 2022. Application of organogel-like structured system as an alternative for reducing saturated fatty acid and replacing fat in milk ice cream. Journal of Food Processing and Preservation 46: e16932. 10.1111/jfpp.16932
Sarfraz, F., Farooq, U., Shafi, A., Hayat, Z., Akram, K. and Rehman, H.U., 2019. Hypolipidaemic effects of synbiotic yogurt in rabbits. International Journal of Dairy Technology 72: 545–550. 10.1111/1471-0307.12618
Schädle, C., 2022. Impact of fat replacers on the rheological, tribological, and aroma release properties of reduced-fat model emulsion systems and processed cheese. Doctoral Dissertation, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Sharma, H., Ozogul, F., Bartkiene, E. and Rocha, J.M., 2021. Impact of lactic acid bacteria and their metabolites on the techno-functional properties and health benefits of fermented dairy products. Critical Reviews in Food Science and Nutrition 30: 1–23. 10.1080/10408398.2021.2007844
Shi, T.X. and Li, Y., 2021. Producing high Fischer ratio peptides from milk protein and its application in infant formula milk powder. Quality Assurance and Safety of Crops and Foods 13(1): 49–58. 10.15586/qas.v13.i1.808
Singh, R.B., Fedacko, J., Saboo, B., Niaz, M., Maheshwari, A., Verma, N., et al. 2017. Association of higher omega-6/omega-3 fatty acids in the diet with higher prevalence of metabolic syndrome in north India. MOJ Public Health 6(6): 193. 10.15406/mojph.2017.06.00193
Sivamaruthi, B.S., Kesika, P. and Chaiyasut, C., 2019. A mini-review of human studies on cholesterol-lowering properties of probiotics. Scientia Pharmaceutica 87(4): 26. 10.3390/scipharm87040026
Sohag, M.S.U., Paul, M., Al-Bari, M.A.A., Wahed, M.I.I. and Khan, M.R.I., 2019. Potential antidiabetic activities of probiotic strains, L. acidophilus and L. bulgaricus against fructose-fed hyperglycemic rats. Food and Nutrition Sciences 10(12): 1419–1432. 10.4236/fns.2019.1012101
Sperry, M.F., Silva, H.L.A., Balthazar, C.F., Esmerino, E.A., Verruck, S., Prudencio, E.S., et al. 2018. Probiotic Minas Frescal cheese added with L. casei 01: physicochemical and bioactivity characterization and effects on hematological/biochemical parameters of hypertensive overweighted women–a randomized double-blind pilot trial. Journal of Functional Foods 45: 435–443. 10.1016/j.jff.2018.04.015
Sun, J. and Buys, N., 2015. Effects of probiotics consumption on lowering lipids and CVD risk factors: a systematic review and meta-analysis of randomized controlled trials. Annals of Medicine 47(6): 430–440. 10.3109/07853890.2015.1071872
Tang, Z.X., Ying, R.F., Lv, B.F., Yang, L.H., Xu, Z., Yan, L.Q., et al. 2021. Flaxseed oil: extraction, health benefits and products. Quality Assurance and Safety of Crops and Foods 13: 1–19. 10.15586/qas.v13i1.783
Tanger, C., Utz, F., Spaccasassi, A., Kreissl, J., Dombrowski, J., Dawid, C., et al. 2022. Influence of pea and potato protein microparticles on texture and sensory properties in a fat-reduced model milk dessert. ACS Food Science & Technology 2(1): 169–179. 10.1021/acsfoodscitech.1c00394
Tekin, E., Sahin, S. and Sumnu, G., 2017. Physicochemical, rheological, and sensory properties of low-fat ice cream designed by double emulsions. European Journal of Lipid Science and Technology 119: 1600505. 10.1002/ejlt.201600505
Tewari, S., David, J. and Gautam, A., 2019. A review on probiotic dairy products and digestive health. Journal of Pharmacognosy and Phytochemistry 8(3): 368–372.
Timilsena, Y.P., Wang, B., Adhikari, R. and Adhikari, B., 2017. Advances in microencapsulation of polyunsaturated fatty acids (PUFAs)-rich plant oils using complex coacervation: a review. Food Hydrocolloids 69: 369–381. 10.1016/j.foodhyd.2017.03.007
Torres, I.C., Amigo, J.M., Knudsen, J.C., Tolkach, A., Mikkelsen, B.Ø. and Ipsen, R., 2018. Rheology and microstructure of low-fat yogurt produced with whey protein microparticles as fat replacer. International Dairy Journal 81: 62–71. 10.1016/j.idairyj.2018.01.004
Ullah, R., Nadeem, M., Imran, M., Khan, M.K., Mushtaq, Z., Asif, M., et al. 2020. Effect of microcapsules of chia oil on ω-3 fatty acids, antioxidant characteristics and oxidative stability of butter. Lipids in Health and Disease 19: 10. 10.1186/s12944-020-1190-5
Vasilopoulou, D., Markey, O., Kliem, K.E., Fagan, C.C., Grandison, A.S., Humphries, D.J., et al. 2020. Reformulation initiative for partial replacement of saturated with unsaturated fats in dairy foods attenuates the increase in LDL cholesterol and improves flow-mediated dilatation compared with conventional dairy: the randomized, controlled replacement of saturated fat in dairy on total cholesterol study. American Journal of Clinical Nutrition 111: 739–748. 10.1093/ajcn/nqz344
Villamil, R.A., Guzmán, M.P., Ojeda-Arredondo, M., Cortés, L.Y., Archila, E.G., Giraldo, A., et al.. 2021. Cheese fortification through the incorporation of UFA-rich sources: a review of recent (2010–2020) evidence. Heliyon 7: e05785. 10.1016/j.heliyon.2020.e05785
Viriato, R.L.S., Queirós, M. de S., Neves, M.I.L., Ribeiro, A.P.B. and Gigante, M.L., 2019. Improvement in the functionality of spreads based on milk fat by the addition of low melting triacylglycerols. Food Research International 120: 432–440. 10.1016/j.foodres.2018.10.082
Wa, Y., Yin, B., He, Y., Xi, W., Huang, Y., Wang, C., et al. 2019. Effects of single probiotic-and combined probiotic-fermented milk on lipid metabolism in hyperlipidemic rats. Frontiers in Microbiology 10: 1312. 10.3389/fmicb.2019.01312
Wang, W., Wang, M., Xu, C., Liu, Z., Gu, L., Ma, J., et al. 2022. Effects of soybean oil body as a milk fat substitute on ice cream: physicochemical, sensory, and digestive properties. Foods 11: 1504. 10.3390/foods11101504
Wherry, B., Barbano, D.M. and Drake, M.A., 2019. Use of acid whey protein concentrate as an ingredient in nonfat cup set-style yogurt. Journal of Dairy Science 102: 8768–8784. 10.3168/jds.2019-16247
Yashini, M., Sunil, C.K., Sahana, S., Hemanth, S.D., Chidanand, D.V. and Rawson, A., 2019. Protein-based fat replacers—a review of recent advances. Food Reviews International 37: 197–223. 10.1080/87559129.2019.1701007
Yin, M., Yang, D., Lai, S. and Yang, H., 2021. Rheological properties of xanthan-modified fish gelatin and its potential to replace mammalian gelatin in low-fat stirred yogurt. LWT–Food Science and Technology 147: 111643. 10.1016/j.lwt.2021.111643
Yousefi, M. and Jafari, S.M., 2019. Recent advances in the application of different hydrocolloids in dairy products to improve their techno-functional properties. Trends in Food Science and Technology 88: 468–483. 10.1016/j.tifs.2019.04.015
Yu, E. and Hu, F.B., 2018. Dairy products, dairy fatty acids, and the prevention of cardiometabolic disease: a review of recent evidence. Current Atherosclerosis Reports 20(5): 1–9. 10.1007/s11883-018-0724-z
Zepeda-Hernández, A., Garcia-Amezquita, L.E., Requena, T. and García-Cayuela, T., 2021. Probiotics, prebiotics, and synbiotics added to dairy products: uses and applications to manage type 2 diabetes. Food Research International 142: 110208. 10.1016/j.foodres.2021.110208
Zhang, R., Han, Y., McClements, D.J., Xu, D. and Chen, S., 2022a. Production, characterization, delivery, and cholesterol-lowering mechanism of phytosterols: a review. Journal of Agricultural and Food Chemistry 70(8): 2483–2494. 10.1021/acs.jafc.1c07390
Zhang, H., Zhang, W., Zeng, X., Zhao, X. and Xu, X., 2022b. Recent progress of fat reduction strategies for emulsion type meat products. Food Materials Research 2(1): 1–10. 10.48130/FMR-2022-0010
Złoch, M., Rafińska, K., Sugajski, M., Buszewska-Forajta, M., Walczak-Skierska, J., Railean, V., et al. 2022. Lacticaseibacillus paracasei as a modulator of fatty acid compositions and vitamin D3 in cream. Foods 11: 1659. 10.3390/foods11111659