Assessment of acrylamide in potato fries, chicken, and bread products in major cities of Pakistan during 2024 and estimation of dietary intake

Main Article Content

Arfa Liaquat
Ghulam Mustafa Kamal
Shahzad Zafar Iqbal

Keywords

Acrylamide, Potato, Chicken, Bread products, Dietary intake evaluation, Cancer risk assessment

Abstract

Acrylamide is a toxin produced when food is heated at or above 120°C. It is a byproduct of heat processing. Acrylamide is produced in foods rich in carbohydrates and starch during roasting, baking, and frying. It is a carcinogen and also has other health hazards for human beings. Therefore, to check the presence and amount of acrylamide in food, multiple samples of chicken, bread, and potato products were collected from different cities in Pakistan and analyzed by using HPLC.  We found acrylamide in almost all samples analyzed. The average amounts 129.07 µg/kg in chicken, 478.85 µg/kg in potatoes, and 112.6 µg/kg in bread samples, with relative standard deviations (RSDs) of less than 7%. The results showed that acrylamide levels differ significantly across food types and sampling areas. The acrylamide exposure rate (µg/kg body weight (BW)) for various age groups was also studied. Although the results suggest that these items may add to total acrylamide intake, it is important to use existing risk assessment frameworks and total dietary exposure when interpreting the observed amounts. Further thorough nutritional and toxicological evaluations are required to more precisely identify the associated health concerns for the Pakistani population, even though the presence of acrylamide merits consideration due to its possible health implications.

Abstract 8 | PDF Downloads 1 XML Downloads 3 HTML Downloads 0

References

Abedini, A.H., Vakili Saatloo, N., Salimi, M., Sadighara, P., Alizadeh Sani, M., Garcia-Oliviera, P., Prieto, M.A., Kharazmi, M.S. and Jafari, S.M. 2024. The role of additives on acrylamide formation in food products: A systematic review. Critical Reviews in Food Science and Nutrition 64(10): 2773. https://doi.org/10.1080/10408398.2022.2126428
Abt, E., Robin, L.P., McGrath, S., Srinivasan, J., DiNovi, M., Adachi, Y. and Chirtel, S. 2019. Acrylamide levels and dietary exposure from foods in the United States, an update based on 2011–2015 data. Food Additives & Contaminants: Part A 36(10): 1475. https://doi.org/10.1080/19440049.2019.1637548
Ahmed, Z.A. and Mohammed, N.K. 2024. Investigating influencing factors on acrylamide content in fried potatoes and mitigating measures: A review. Food Production, Processing and Nutrition 6(1): 24. https://doi.org/10.1186/s43014-023-00212-6
Ahmed, Z.A., Mohammed, N.K. and Hussin, A.S.M. 2023. Acrylamide content and quality characteristics of French fries influenced by different frying methods. Functional Foods in Health and Disease 13(6): 320. https://doi.org/10.31989/ffhd.v13i6.1126
Albedwawi, A.S., Al Sakkaf, R., Yusuf, A., Osaili, T.M., Al-Nabulsi, A., Liu, S.Q., Palmisano, G. and Ayyash, M.M. 2022. Acrylamide elimination by lactic acid bacteria: Screening, optimization, in vitro digestion and mechanism. Microorganisms 10(3): 557. https://doi.org/10.3390/microorganisms10030557
Bellicha, A., Wendeu-Foyet, G., Coumoul, X., Koual, M., Pierre, F., Guéraud, F., Zelek, L., Debras, C., Srour, B. and Sellem, L. 2022. Dietary exposure to acrylamide and breast cancer risk: Results from the NutriNet-Santé cohort. The American Journal of Clinical Nutrition 116(4): 911. https://doi.org/10.1093/ajcn/nqac167
Benisi-Kohansal, S., Salari-Moghaddam, A., Rohani, Z.S. and Esmaillzadeh, A. 2021. Dietary acrylamide intake and risk of women’s cancers: A systematic review and meta-analysis of prospective cohort studies. British Journal of Nutrition 126(9): 1355. https://doi.org/10.1017/S0007114520005255
Bouchon, P. and Dueik, V. 2018. Frying of foods of chapter. In: editor. Fruit Preservation: Novel and Conventional Technologies. Springer: 275. https://doi.org/10.1007/978-1-4939-3311-2_10
Bruno, F., Ledbetter, M., Davies, B., Riedinger, L., Blidi, S., Sturrock, K., McNamara, G., Montague, G. and Fiore, A. 2024. Effect of ultrasound and additives treatment as mitigation strategies to reduce acrylamide formation in potato crisps on industrial scale. Food Science & Technology 197(115876. https://doi.org/10.1016/j.lwt.2024.115876
Bušová, M., Bencko, V., Kromerová, K., Nadjo, I. and Babjaková, J. 2020. Occurrence of acrylamide in selected food products. Central European Journal of Public Health 28(4): 320. https://doi.org/10.21101/cejph.a6430
Cengiz, M.F. and Gündüz, C.P.B. 2013. Acrylamide exposure among Turkish toddlers from selected cereal-based baby food samples. Food and Chemical Toxicology 60 (514-519). https://doi.org/10.1016/j.fct.2013.08.018
Chathiran, W., On-nom, N., Somsong, P., Tiyayon, P., Niranjan, K. and Srichamnong, W. 2024. The efficacy and lipid degradation properties resulting from corncob biochar treatment for acrylamide reduction in reused palm oil. Food Science & Technology 192(115720. https://doi.org/10.1016/j.lwt.2023.115720
Dadar, M., Adel, M., Nasrollahzadeh Saravi, H. and Fakhri, Y. 2017. Trace element concentration and its risk assessment in common kilka (Clupeonella cultriventris caspia Bordin, 1904) from southern basin of Caspian Sea. Toxin Reviews 36(3): 222. https://doi.org/10.1080/15569543.2016.1274762
Dastmalchi, F., Razavi, S.H., Faraji, M. and Labbafi, M. 2016. Effect of Lactobacillus casei-casei and Lactobacillus reuteri on acrylamide formation in flat bread and Bread roll. Journal of Food Science and Technology 53(3): 1531. https://doi.org/10.1007/s13197-015-2118-3
Demirok Soncu, E., Haskaraca, G. and Kolsarıcı, N. 2018. Presence of acrylamide and heterocyclic aromatic amines in breaded chicken meat products and dietary exposure of Turkish population from Ankara based on the food frequency questionnaire study. European Food Research and Technology 244(3): 501. https://doi.org/10.1007/s00217-017-2976-1
Deshmukh, R. 2019. The effect of repeatedly cooking oils on health and wealth of a country: A short communication. Journal of Food Processing and Technology. 10(8): 1. https://doi.org/10.35248/2157-7110.19.10.807
EFSA. 2015. Scientific opinion on acrylamide in food. EFSA Journal. 13 (6) (4104). https://doi.org/10.2903/j.efsa.2015.4104
El-Sayed, A.A., Abdelhady, M.M., Jaafari, S.A., Alanazi, T.M. and Mohammed, A.S. 2023. Impact of some enzymatic treatments on acrylamide content in biscuits. Processes 11(4): 1041. https://doi.org/10.3390/pr11041041
Elias, A., Roasto, M., Reinik, M., Nelis, K., Nurk, E. and Elias, T. 2017. Acrylamide in commercial foods and intake by infants in Estonia. Food Additives & Contaminants: Part A 34(11): 1875. https://doi.org/10.1080/19440049.2017.1347283
Elsheshtawy, M., Salem, A., Elsabagh, R. and Sabeq, I. 2022. Acrylamide Assessment in meat products sold in Al-Qalubyia, Egypt, and the impacts of different cooking methods on their levels. Benha Journal of Applied Sciences 7(5): 211. https://doi.org/10.21608/bjas.2022.283023
Erickson, M.D., Yevtushenko, D.P. and Lu, Z.X. 2023. Oxidation and thermal degradation of oil during frying: A review of natural antioxidant use. Food Reviews International 39(7): 4665. https://doi.org/10.1080/87559129.2022.2039689
Eslamizad, S., Kobarfard, F., Tsitsimpikou, C., Tsatsakis, A., Tabib, K. and Yazdanpanah, H. 2019. -16. Food and Chemical Toxicology 126 (162-168). https://doi.org/10.1016/j.fct.2019.02.019
Esposito, F., Nardone, A., Fasano, E., Triassi, M. and Cirillo, T. 2017. Determination of acrylamide levels in potato crisps and other snacks and exposure risk assessment through a margin of exposure approach. Food and Chemical Toxicology 108(249-256). https://doi.org/10.1016/j.fct.2017.08.006
FAO/WHO. 2010. Evaluation of certain food contaminants.Seventy-second report of the joint FAo/WHO expert committee on food additives. http://www.fao.org/ag/agn/agns/jecfa%7B_%7Dindex%7B_%7Den.asp.
Fathabad, A.E., Shariatifar, N., Moazzen, M., Nazmara, S., Fakhri, Y., Alimohammadi, M., Azari, A. and Khaneghah, A.M. 2018. Determination of heavy metal content of processed fruit products from Tehran's market using ICP-OES: A risk assessment study. Food and Chemical Toxicology. 115(436-446). https://doi.org/10.1016/j.fct.2018.03.044
Fikry, M., Khalifa, I., Sami, R., Khojah, E., Ismail, K.A. and Dabbour, M. 2021. Optimization of the frying temperature and time for preparation of healthy falafel using air frying technology. Foods 10(11): 2567. https://doi.org/10.3390/foods10112567
Filippini, T., Halldorsson, T.I., Capitao, C., Martins, R., Giannakou, K., Hogervorst, J., Vinceti, M., Åkesson, A., Leander, K. and Katsonouri, A. 2022. Dietary acrylamide exposure and risk of site-specific cancer: A systematic review and dose-response meta-analysis of epidemiological studies. Frontiers in Nutrition. 9(875607. https://doi.org/10.3389/fnut.2022.875607
Ghasemidehkordi, B., Malekirad, A.A., Nazem, H., Fazilati, M., Salavati, H., Shariatifar, N., Rezaei, M., Fakhri, Y. and Khaneghah, A.M. 2018. Concentration of lead and mercury in collected vegetables and herbs from Markazi province, Iran: A non-carcinogenic risk assessment. Food and Chemical Toxicology. 113(204-210). https://doi.org/10.1016/j.fct.2018.01.048
Gökmen, V. 2023. Acrylamide in thermally processed potato products. Potato Research 66(4): 1315. https://doi.org/10.1007/s11540-023-09634-8
Govindaraju, I., Sana, M., Chakraborty, I., Rahman, M.H., Biswas, R. and Mazumder, N. 2024. Dietary acrylamide: A detailed review on formation, detection, mitigation, and its health impacts. Foods 13(4): 556. https://doi.org/10.3390/foods13040556
Halford, N.G. 2018. Managing acrylamide at the agricultural stage: Variety selection, crop management, and the prospects for solving the acrylamide problem through plant breeding and biotechnology.In: Encyclopedia of Food Chemistry, 1 (559-568). https://doi.org/10.1016/B978-0-08-100596-5.21821-0
Halford, N.G., Raffan, S. and Oddy, J. 2022. Progress towards the production of potatoes and cereals with low acrylamide-forming potential. Current Opinion in Food Science 47(100887. https://doi.org/10.1016/j.cofs.2022.100887
Hamzalıoğlu, A. and Gökmen, V. 2019. Formation of acrylamide in thermally processed foods and its reactionsduring in vitro digestion of chapter. In: editor. Food-Borne Toxicants: Formation, Analysis, and Toxicology. ACS Publications: 45. https://doi.org/10.1021/bk-2019-1306.ch004
Heshmati, A., Ghadimi, S., Khaneghah, A.M., Barba, F.J., Lorenzo, J.M., Nazemi, F. and Fakhri, Y. 2018. Risk assessment of benzene in food samples of Iran's market. Food and Chemical Toxicology. 114(278. https://doi.org/10.1016/j.fct.2018.02.043
Hidayah, J.N., Razis, A.F.A., Jambari, N.N., Chai, L.C., You, L. and Sanny, M. 2024. Dietary exposure to acrylamide among the Malaysian adult population. Food and Chemical Toxicology. 185(114502. https://doi.org/10.1016/j.fct.2024.114502
Hirvonen, T., Jestoi, M., Tapanainen, H., Valsta, L., Virtanen, S.M., Sinkko, H., Kronberg-Kippilä, C., Kontto, J., Virtamo, J. and Simell, O. 2011. Dietary acrylamide exposure among Finnish adults and children: The potential effect of reduction measures. Food Additives & Contaminants: Part A 28(11): 1483. https://doi.org/10.1080/19440049.2011.593559
IRIS. 2010. Acrylamide ; CASRN 79-06-1. IRIS Assessment. https://cfpub.epa.gov/ncea/iris2/chemicalLanding.cfm?substance_nmbr=286.
Jahanbakhsh, M., Afshar, A., Momeni Feeli, S., Pabast, M., Ebrahimi, T., Mirzaei, M., Akbari-Adergani, B., Farid, M. and Arabameri, M. 2021. Probabilistic health risk assessment (Monte Carlo simulation method) and prevalence of aflatoxin B1 in wheat flours of Iran. International Journal of Environmental Analytical Chemistry 101(8): 1074. https://doi.org/10.1080/03067319.2019.1676421
Jeong, H., Hwang, S. and Kwon, H. 2020. Survey for acrylamide in processed foods from Korean market and individual exposure estimation using a non-parametric probabilistic model. Food Additives & Contaminants: Part A 37(6): 916. https://doi.org/10.1080/19440049.2020.1746410
Kafouris, D., Stavroulakis, G., Christofidou, M., Iakovou, X., Christou, E., Paikousis, L., Christodoulidou, M., Ioannou-Kakouri, E. and Yiannopoulos, S. 2018. Determination of acrylamide in food using a UPLC–MS/MS method: Results of the official control and dietary exposure assessment in Cyprus. Food Additives & Contaminants: Part A 35(10): 1928. https://doi.org/10.1080/19440049.2018.1508893
Kaur, N. and Halford, N.G. 2023. Reducing the risk of acrylamide and other processing contaminant formation in wheat products. Foods 12(17): 3264. https://doi.org/10.3390/foods12173264
Koszucka, A. and Nowak, A. 2019. Thermal processing food-related toxicants: A review. Critical Reviews in Food Science and Nutrition. 59(22): 3579. https://doi.org/10.1080/10408398.2018.1500440
Kumari, A., Bhattacharya, B., Agarwal, T., Paul, V. and Chakkaravarthi, S. 2022. Integrated approach towards acrylamide reduction in potato-based snacks: A critical review. Food Research International 156 (111172). https://doi.org/10.1016/j.foodres.2022.111172
Lambert, M., Inthavong, C., Hommet, F., Leblanc, J.C., Hulin, M. and Guerin, T. 2018. Levels of acrylamide in foods included in ‘the first French total diet study on infants and toddlers’. Food Chemistry. 240(997-1004). https://doi.org/10.1016/j.foodchem.2017.08.035
Lee, J.S., Han, J.W., Jung, M., Lee, K.W. and Chung, M.S. 2020. Effects of thawing and frying methods on the formation of acrylamide and polycyclic aromatic hydrocarbons in chicken meat. Foods 9(5): 573. https://doi.org/10.3390/foods9050573
Lee, S. and Kim, H.J. 2020. Dietary exposure to acrylamide and associated health risks for the Korean population. International Journal of Environmental Research and Public Health. 17(20): 7619. https://doi.org/10.3390/ijerph17207619
Maan, A.A., Anjum, M.A., Khan, M.K.I., Nazir, A., Saeed, F., Afzaal, M. and Aadil, R.M. 2022. Acrylamide formation and different mitigation strategies during food processing– A review. Food Reviews International 38(1): 70. https://doi.org/10.1080/87559129.2020.1719505
Madani-Tonekaboni, M., Rafiei Nazari, R., Mirzamohammadi, S., Abdolshahi, A., Abbasi-bastami, N. and Arabameri, M. 2019. Monitoring and risk assessment of lead and cadmium in milks from east of Iran using Monte Carlo simulation method. Nutrition and Food in Health and Disease 6(2): 29. https://doi.org/10.29252/nfsr.6.2.29
Manzoor, S., Masoodi, F., Rashid, R., Wani, S.M., Naqash, F. and Ahmad, M. 2023. Advances in vacuum frying: Recent developments and potential applications. Journal of Food Process Engineering 46(2): e14219. https://doi.org/10.1111/jfpe.14219
Mesías, M., Delgado-Andrade, C., Holgado, F. and Morales, F.J. 2019. Acrylamide content in French fries prepared in food service establishments. Food Science & Technology 100(83. https://doi.org/10.1016/j.lwt.2018.10.050
Michalak, J., Czarnowska-Kujawska, M., Klepacka, J. and Gujska, E. 2020. Effect of microwave heating on the acrylamide formation in foods. Molecules 25(18): 4140. https://doi.org/10.3390/molecules25184140
Mojska, H., Gielecińska, I., Szponar, L. and Ołtarzewski, M. 2010. Estimation of the dietary acrylamide exposure of the Polish population. Food and Chemical Toxicology 48(8–9): 209Khaneghah, M. A., Fakhri, Y., Nematollahi, A., Seilani, F. and Vasseghian, Y. 2022. The concentration of acrylamide in different food products: A global systematic review, meta-analysis, and meta-regression. Food Reviews International 38(6): 1286. https://doi.org/10.1080/87559129.2020.1791175
Mucci, L.A. and Wilson, K.M. 2008. Acrylamide intake through diet and human cancer risk. Journal of Agricultural and Food Chemistry 56(15): 6013. https://doi.org/10.1021/jf703747b
Naji, Y.A.M., Alam, M., Bashir, S. and Kadir, N.H.A. 2025. Bibliometric exploration of the state of the art on acrylamide and glycidamide in food safety. Beni-Suef University Journal of Basic and Applied Sciences 14(1): 52. https://doi.org/10.1186/s43088-025-00639-5
Negoiță, M., Mihai, A.L. and Horneț, G.A. 2022. Influence of water, NaCl and citric acid soaking pre-treatments on acrylamide content in French fries prepared in domestic conditions. Foods. 11(9): 1204. https://doi.org/10.3390/foods11091204
Pacetti, D., Gil, E., Frega, N.G., Álvarez, L., Dueñas, P., Garzón, A. and Lucci, P. 2015. Acrylamide levels in selected Colombian foods. Food Additives & Contaminants: Part B 8(2): 99. https://doi.org/10.1080/19393210.2014.995236
Pandiselvam, R., Süfer, Ö., Özaslan, Z.T., Gowda, N.N., Pulivarthi, M.K., Charles, A.P.R., Ramesh, B., Ramniwas, S., Rustagi, S. and Jafari, Z. 2024. Acrylamide in food products: Formation, technological strategies for mitigation, and future outlook. Food Frontiers 5(3): 1063. https://doi.org/10.1002/fft2.368
Peivasteh-Roudsari, L., Karami, M., Barzegar-Bafrouei, R., Samiee, S., Karami, H., Tajdar-Oranj, B., Mahdavi, V., Alizadeh, A.M., Sadighara, P. and Oliveri Conti, G. 2024. Toxicity, metabolism, and mitigation strategies of acrylamide: A comprehensive review. International Journal of Environmental Health Research 34(1): 1. https://doi.org/10.1080/09603123.2022.2123907
Perestrelo, S., Schwerbel, K., Hessel-Pras, S., Schäfer, B., Kaminski, M., Lindtner, O. and Sarvan, I. 2024. Results of the BfR MEAL Study: Acrylamide in foods from the German market with highest levels in vegetable crisps. Food Chemistry: X. 22(101403. https://doi.org/10.1016/j.fochx.2024.101403
Pietropaoli, F., Pantalone, S., Cichelli, A. and d'Alessandro, N. 2022. Acrylamide in widely consumed foods–A review. Food Additives & Contaminants: Part A 39(5): 853. https://doi.org/10.1080/19440049.2022.2046292
Rahman, N.S.A.A. and Malik, N.H. 2023. Comparative study between deep-fat frying and air frying of sweet potato perkedel. Enhanced Knowledge in Sciences and Technology 3(2): 344.
Razia, S., Bertrand, M., Klaus, V. and Meinolf, G. 2016. Investigation of acrylamide levels in branded biscuits, cakes and potato chips commonly consumed in Pakistan. International Food Research Journal 23(5): 2187-2192.
Samiee, S., Fakhri, Y., Sadighara, P., Arabameri, M., Rezaei, M., Nabizadeh, R., Shariatifar, N. and Mousavi Khaneghah, A. 2020. The concentration of polycyclic aromatic hydrocarbons (PAHs) in the processed meat samples collected from Iran’s market: A probabilistic health risk assessment study. Environmental Science and Pollution Research. 27(17): 21126. https://doi.org/10.1007/s11356-020-08413-z
Sansano, M., Heredia, A., Peinado, I. and Andrés, A. 2017. Dietary acrylamide: What happens during digestion. Food Chemistry. 237(58-64). https://doi.org/10.1016/j.foodchem.2017.05.104
Seilani, F., Shariatifar, N., Nazmara, S., Khaniki, G.J., Sadighara, P. and Arabameri, M. 2021. The analysis and probabilistic health risk assessment of acrylamide level in commercial nuggets samples marketed in Iran: Effect of two different cooking methods. Journal of Environmental Health Science and Engineering 19(1): 465. https://doi.org/10.1007/s40201-021-00619-8
Shahrbabki, P.E., Hajimohammadi, B., Shoeibi, S., Elmi, M., Yousefzadeh, A., Conti, G.O., Ferrante, M., Amirahmadi, M., Fakhri, Y. and Khaneghah, A.M. 2018. Probabilistic non-carcinogenic and carcinogenic risk assessments (Monte Carlo simulation method) of the measured acrylamide content in Tah-dig using QuEChERS extraction and UHPLC-MS/MS. Food and Chemical Toxicology 118(361-370). https://doi.org/10.1016/j.fct.2018.05.038
Shariatifar, N., Rezaei, M., Alizadeh Sani, M., Alimohammadi, M. and Arabameri, M. 2020. Assessment of rice marketed in Iran with emphasis on toxic and essential elements; effect of different cooking methods. Biological Trace Element Research 198(2): 721. https://doi.org/10.1007/s12011-020-02110-1
Sharif, R., Shahar, S., Rajab, N.F. and Fenech, M. 2022. Dietary pattern, genomic stability and relative cancer risk in Asian food landscape. Nutrition and Cancer 74(4): 1171. https://doi.org/10.1080/01635581.2021.1952627
Song, X., Sui, X. and Jiang, L. 2023. Protection function and mechanism of rosemary (Rosmarinus officinalis L.) extract on the thermal oxidative stability of vegetable oils. Foods 12(11): 2177. https://doi.org/10.3390/foods12112177
Taghizadeh, S.F., Badibostan, H., Hayes, A.W., Giesy, J.P. and Karimi, G. 2021. Residues levels of pesticides in walnuts of Iran and associated health risks. Human and Ecological Risk Assessment: An International Journal 27(1): 191. https://doi.org/10.1080/10807039.2019.1704619
Taghizadeh, S.F., Goumenou, M., Rezaee, R., Alegakis, T., Kokaraki, V., Anesti, O., Sarigiannis, D.A., Tsatsakis, A. and Karimi, G. 2019. Cumulative risk assessment of pesticide residues in different Iranian pistachio cultivars: Applying the source specific HQS and adversity specific HIA approaches in Real Life Risk Simulations (RLRS) Toxicology Letters 313(91-100). https://doi.org/10.1016/j.toxlet.2019.05.019
Tareke, E., Rydberg, P., Karlsson, P., Eriksson, S. and Törnqvist, M. 2002. Analysis of acrylamide, a carcinogen formed in heated foodstuffs. Journal of Agricultural and Food Chemistry 50(17): 4998. https://doi.org/10.1021/jf020302f
Verma, V., Singh, V., Chauhan, O.P. and Yadav, N. 2023. Comparative evaluation of conventional and advanced frying methods on hydroxymethylfurfural and acrylamide formation in French fries. Innovative Food Science & Emerging Technologies 83(103233. https://doi.org/10.1016/j.ifset.2022.103233
Virk-Baker, M.K., Nagy, T.R., Barnes, S. and Groopman, J. 2014. Dietary acrylamide and human cancer: A systematic review of literature. Nutrition and Cancer 66(5): 774. https://doi.org/10.1080/01635581.2014.916323
Yu, W.Z., Shen, P., Lim, I., Shi, R.R.S., Cai, M., Chin, Y.S., Tay, A.J., Ang, W.M., Er, J.C. and Lim, G.S. 2023. Occurrence and dietary exposure to acrylamide from foods consumed within and outside main meals in Singapore. Foods 12(16): 3022. https://doi.org/10.3390/foods12163022
Zhang, X., Zhang, M. and Adhikari, B. 2020. Recent developments in frying technologies applied to fresh foods. Trends in Food Science & Technology. 98(68-81). https://doi.org/10.1016/j.tifs.2020.02.007
Zhou, X., Duan, M., Gao, S., Wang, T., Wang, Y., Wang, X. and Zhou, Y. 2022. A strategy for reducing acrylamide content in wheat bread by combining acidification rate and prerequisite substance content of Lactobacillus and Saccharomyces cerevisiae. Current Research in Food Science 5(1054-1060). https://doi.org/10.1016/j.crfs.2022.06.005