Incidents and impacts of unwanted chemicals in food and feeds
Main Article Content
Keywords
contaminants, feed, food, incidents, residues, socio-economic impact, unwanted chemicals
Abstract
Introduction Assessing the significance of unwanted chemicals in food is problematic. The evaluation of cause and effect of many unwanted chemicals in foods and feed is complicated by cumulative low doses and the delayed onset of symptoms. Objectives This paper reviews incidents of unwanted chemicals in food and feed where people were adversely affected, or where an unusually high level was found and traced to a particular event and for which some socioeconomic impact information was available. Methods Incidents and impacts were
identified from the peer-reviewed scientific literature, from governmental websites, from Internet searches, from trades and consumer associations and media releases. Results Some 44 major events were identified from 1888 to date. Information on the impacts of these incidents is fragmentary and unsystematic, ranging from thousands of Euros to meet the cost of monitoring analysis, to many millions of Euros due to court prosecutions, bankruptcy, product disposal, revenue loss compensation, damage to brand or reputation, or loss of life. Conclusion An evolution is apparent from the evidence of human health effects/toxicity data, igniting legal action and legislative changes, to the implementation of monitoring and surveillance alerts to ensure that risks are identified and managed – if possible – before they reach the consumer.
References
Bakir F., Damluji S.F., Amin Zaki I. (1973) Methylmercury poisoning in Iraq: an interuniversity report.Science,181,230–241.
BBC News. (2006)Food scare costs company £5,000. Available athttp://newsvote.bbc.co.uk/mpapps/pagetools/print/news.bbc.co.uk/2/hi/uk_news/england/essex/4744794.stm[Last accessed 20 March 2012].
BBC News. (2010)Minister heard feed toxic on TV. Available athttp://newsvote.bbc.co.uk/mpapps/pagetools/print/news.bbc.co.uk/2/hi/uk_news/northern_ireland/8567267.stm?ad=1 [Last accessed 20 March 2012].
Bhat R., Ramakrishna Y., Beedu S.R., Munshi K.L. (1989)Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat products in Kashmir valley, India.Lancet,1, 35–37.
Bhat R.V., Shetty P.H., Amruth R.P., Sudershan R.V. (1997) A foodborne disease outbreak due to the consumption of moldy sorghum and maize containing fumonisin mycotoxins.Journal of Toxicology – Clinical Toxicology,35,249–255.
Covaci A., Voorspoels S., Schepens P., Jorens P., Blust R., NeelsH. (2008) The Belgian PCB/dioxin crisis-8 years later. An overview.Environmental Toxicology and Pharmacology,25,164–170.
Crawford B., Cowell C., Emder P., Learoyd D., Chua E., Sinn J., Jack M. (2010) Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Medical Journal of Australia,193, 413–415.
Crews H.M., Baxter M.J., Bigwood T., Burrell J.A., Owen L.M., Robinson C., Wright C., Massey R.C. (1992) Lead in feed incident – Multi-element analysis of cattle feed and tissues by inductively coupled plasma-mass spectrometry and co-operative quality assurance scheme for lead analysis of milk.Food Additives and Contaminants,9, 365–378.
D’Mello J., Duffus C., Duffus J., eds (1991)Toxic Substances interop Plants. The Royal Society of Chemistry, Cambridge, UK.
Dakeishi M., Murata K., Grandjean P. (2006) Long-term consequences of arsenic poisoning during infancy due to contaminated milk powder.Environmental Health: A GlobalAccess Science Source,5, Article No. 31.
Demeke T., Kidane Y., Wuhib E. (1979) Ergotism – A report onan epidemic, 1977–78.Ethiopian Medical Journal,17,107–113.
Dipietro B., Fiorillo J. (2005)Stolt takes malachite green hit.Available from http://www.intrafish.no/multimedia/archive/00006/pdf20050706_6267a.pdf [Last accessed 13 January 2010. Unable to accessed 20 March 2012].
Dunckel A.E. (1975) An updating on the polybrominated biphenyl disaster in Michigan.JAVMA,167, 838–841.
Dungal N. (1961) The special problem of stomach cancer in Iceland.JAMA,178, 789–798.
Editorial. (2009) Melamine and food safety in China.TheLancet,373, 353.
Firestone D. (1973) Etiology of chick edema disease.Environmental Health Perspectives,5, 59–66.
Food Production Daily. (2003)FSA sound alarm over nitrofurans in Portugese chickens. Available at http://www.foodproductiondaily.com/content/view/print/136563[Last accessed 20 March 2012].
Fries G.F. (1985) The PBB episode in Michigan: an overall appraisal.Critical Reviews in Toxicology,16, 105–156.
Friends of Clayoquot Sound. (2005)Cancer-contaminated BCfarmed salmon must be destroyed. Available at http://www.focs.ca/news/050604.asp [Last accessed 21 March 2012].
FSA. (2001)Olive-pomace oil: your questions answered. Availableat http://www.food.gov.uk/multimedia/faq/olivepomoilqa/[Last accessed 20 March 2012].
FSA. (2002a)Chinese honey: your questions answered. Available at http://www.food.gov.uk/multimedia/faq/47750/?view=printerfriendly [Last accessed 20 March 2012].
FSA. (2002b)Survey reveals details of test for nitrofuran drugs in chicken. Available at http://www.food.gov.uk/news/newsarchive/2002/apr/57091 [Last accessed 20 March 2012].
FSA. (2002c)Your questions answered: nitrofurans in shrimps and prawns. Available at http://www.food.gov.uk/multimedia/faq/51434 [Last accessed 20 March 2012].
FSA. (2003)Illegal drug residues found in Portuguese chickens.Available at http://www.reading.ac.uk/foodlaw/news/uk-03018.htm [Last accessed 20 March 2012].
FSA. (2004)Agency warns consumers about chicken contaminated with a banned veterinary medicine. Available at http://www.reading.ac.uk/foodlaw/news/uk-04042.htm [Lastaccessed 20 March 2012].
FSA. (2005a)Action taken to remove illegal dye found in wide range of foods on sale in UK. Available at http://www.food.gov.uk/news/newsarchive/2005/feb/worcester[Last accessed 20 March 2012].
FSA. (2005b)Sudan I consolidated product list. Available athttp://www.food.gov.uk/multimedia/pdfs/sudanlistno.pdf[Last accessed 20 March 2012].
FSA. (2006)Spice firm fined over Sudan I in curry powder. Available at http://www.food.gov.uk/news/pressreleases/2006/feb/spicefilmsudani?view=printerfriendly [Last accessed 20 March 2012].
FSA. (2008)Principles for preventing and responding to food incidents. Available at http://www.food.gov.uk/foodindustry/guidancenotes/incidentsguidance/principlesdoc [Lastaccessed 20 March 2012].
FSA. (2010)Annual report of incidents 2010. Available athttp://www.food.gov.uk/multimedia/pdfs/publication/annualreportofincidents2010.pdf [Last accessed 20 March 2012].
FSAI Food Safety Authority of Ireland. (2009)FSAI News, January/February ‘09, Irish Dioxin Crisis. Available at http://www.fsai.ie/uploadedFiles/News_Centre/Newsletters/Newsletters_Listing/FINAL(8).pdf [Last accessed 20 March 2012].
George T.S. (2002)Minamata: Pollution and the Struggle for Democracy in Postwar Japan. Harvard University Asia Center, Cambridge, MA, USA.
Gossner C.M.E., Schlundt J., Embarek P.B., Hird S., Lo-Fo-Wong D., Beltran J.J.O., Teoh K.N., Tritscher A. (2009)The melamine incident: implications for international food and feed safety.Environmental Health Perspectives,117,1803–1808.
GovernmentNews. (2001)FSA acts to withdraw Spanish olive-pomace oils. Available at http://www.gov-news.org/gov/uk/news/fsa_acts_to_withdraw_spanish_olive_pomace/7741.html [Last accessed 20 March 2012].
Harrington R. (2011)Dioxin-contaminated liquid egg distributed in UK, Contamination worse than feared in German dioxin scandal. Available at http://www.foodnavigator.com/content/view/print/351701 [Last accessed 20 March 2012].
Health-Canada. (2004)Chloramphenicol in honey. Available at http://www.hc-sc.gc.ca/dhp-mps/vet/faq/faq_chloramphenicol_honey-miel-eng.php [Last accessed 20 March 2012].
Heatley C. (2008)Irish pig producers face EU100 million recall bill (Update2). Available at http://www.bloomberg.com/apps/news?pid=21070001&sid=aiqFAzI5bXZ8 [Last accessed 20 March 2012].
Hoffman C.S., Small C.M., Blanck H.M., Tolbert P., Rubin C., Marcus M. (2007) Endometriosis among women exposed to polybrominated biphenyls. Annals of Epidemiology,17,503–510.
Hoogenboom R., Bovee T., Portier L., Bor G., Van Der Weg G., Onstenk C., Traag W. (2004) The German bakery waste incident; use of a combined approach of screening and confirmation for dioxins in feed and food.Talanta,63,1249–1253.
Hsu S.T., Ma C.I., Hsu S.K.H. (1985) Discovery and epidemiology of PCB poisoning in Taiwan: a four-year follow-up.Environmental Health Perspectives,59, 5–10.
Hylander L.D., Goodsite M.E. (2006) Environmental costs of mercury pollution.Science of the Total Environment,368,352–370.
JECFA. (1993)Solanine and Chaconine (WHO Food AdditivesSeries 30). World Health Organization, Geneva.
JECFA. (2001)T-2 and HT-2 Toxins. Safety Evaluation of certain Food Additives and Contaminants.WHO FoodAdditive Series 47. World Health Organization, Geneva.
Joseph A.D., Terrell M.L., Small C.M., Cameron L.L., Marcus M.(2009) Assessing inter-generational transfer of a brominated flame retardant.Journal of Environmental Monitoring,11,802–807.
Kasuya M., Teranishi H., Aoshima K., Katoh T., Horiguchi H., Morikawa Y., Nishijo M., Iwata K. (1992) Water pollution by cadmium and the onset of Itai-Itai disease.Water Science andTechnology,26, 149–156.
Klatsky A.L. (2006) Re: ‘Arsenic exposure and cardiovascular disease: a systematic review of the epidemiologic evidence’[1].American Journal of Epidemiology,164, 194–195.
Krishnamachari K., Bhat R. (1976) Poisoning by Ergoty Bajra(pearl millet) in man.Indian Journal of Medical Research,64,1624–1628.
Kuratsune M., Yoshimura H., Hori Y., Okumura M., Masuda Y.(1996)Yusho, A Human Disaster Caused by PCBs and related compounds. Kyushu University Press, Fukuoka.
Lijinsky W. (1999) N-Nitroso compounds in the diet.MutationResearch – Genetic Toxicology and Environmental Mutagenesis,443, 129–138.
Malisch R. (2000) Increase of the PCDD/F-contamination of milk, butter and meat samples by use of contaminated citrus pulp.Chemosphere,40, 1041–1053.
Massey R., Hamlet C. (2007) Chloropropanol contaminants in food – The story continues.Food Science and Technology,21,32–34.
Matthews A. (2009)Food safety – the Irish pork dioxin crisis revisited. Available at http://capreform.eu/food-crisis-the-irish-pork-dioxin-crisis-revisited/ [Lastaccessed 20 March 2012].
McMillan M., Thompson J.C. (1979) An outbreak of suspected solanine poisoning in schoolboys: examination of criteria of solanine poisoning.Quarterly Journal of Medicine,48,227–243.
Mocarelli P. (2001) Seveso: a teaching story.Chemosphere,43,391–402.
Murray-West R. (2005)How the Sudan 1 scare started a blamechain. Available at http://www.telegraph.co.uk/finance/2906651/How-the-Sudan-1-scare-started-a-blame-chain.html[Last accessed 20 March 2012].
New Zealand Food Safety Authority (NZFSA). (2004a)Source of lead-contaminated cornflour traced. Available athttp://www.foodsafety.govt.nz/elibrary/industry/Source_Lead-Nzfsa_Confident.htm [Last accessed 20 March 2012].
New Zealand Food Safety Authority (NZFSA). (2004b)Source of lead-contaminated cornflour traced. Available at http://www.nzfsa.govt.nz/publications/media-releases/2004/2004-07-29-cornflour.htm?print [Last accessed 20 March 2012].
O’Connell R., Parkin L., Manning P., Bell D., Herbison P., Holmes J. (2005) A cluster of thyrotoxicosis associated with consumption of a soy milk product.Australian and NewZealand Journal of Public Health,29, 511–512.
Office of Technology Assessment. (1979)environmental contaminants in Food. Congress of the United States, Washington, DC.
Pennington J.A., Gunderson E.L. (1987) History of the Food and Drug Administration’s total diet study – 1961 to 1987.Journal of the Association of Official Analytical Chemists,70,772–782.
Poms R.E., Astley S. (2011) MoniQA: an update of the EU funded Network of Excellence in 2011.QAS – QualityAssurance and Safety of Crops & Foods,2, 89–102.
Pruser K.N., Flynn N.E. (2011) Acrylamide in health and disease.Frontiers in bioscience (Scholar edition),3, 41–51.
Ragona M., Mazzocchi M., Zanoli A., Alldrick A.J., Solfrizzo M., Van Egmond H.P. (2011) Testing a toolbox for impact assessment of food safety regulations: maximum levels for T-2 and HT-2 toxins in the European Union.Quality Assurance and Safety of Crops & Foods,3,12–23.
RASFF. (2011)Rapid alert system for food and feed. Available at http://ec.europa.eu/food/food/rapidalert/rasff_legal_basis_en.htm [Last accessed 20 March 2012].
Reynolds E.S. (1901) An account of the epidemic outbreak of arsenical poisonings occurring in beer-drinkers in the north of England and the midland counties in 1900.The Lancet,1,166–170.
Rose M., Thomson B., Jensen A.-M., Giorgi L., Schulz C.(2009) Food monitoring and control for environmental contaminants.Quality Assurance and Safety of Crops & Foods,1, 160–169.
Scott W.G., Scott H.M., Lake R.J., Baker M.G. (2000) Economiccost to New Zealand of foodborne infectious disease.NewZealand Medical Journal,113, 281–284.
Small C.M., Cheslack-Postava K., Terrell M., Blanck H.M., Tolbert P., Rubin C., Henderson A., Marcus M. (2007) Risk of spontaneous abortion among women exposed to polybrominated biphenyls.Environmental Research,105,247–255.
Sweeney A.M., Symanski E. (2007) The influence of age at exposure to PBBs on birth outcomes.EnvironmentalResearch,105, 370–379.
Tandon H.D., Tandon B.N., Ramalingaswami V. (1978)Epidemic of toxic hepatitis in India of possible mycotoxic origin.Archives of Pathology and Laboratory Medicine,102,372–376.
Tareke E., Rydberg P., Karlsson P., Eriksson S., Törnqvist M.(2002) Analysis of acrylamide, a carcinogen formed in heated foodstuffs.Journal of Agricultural and Food Chemistry,50, 4998–5006.
Terrell M.L., Manatunga A.K., Small C.M., Cameron L.L., WirthJ., Blanck H.M., Lyles R.H., Marcus M. (2008) A decay model for assessing polybrominated biphenyl exposure among women in the Michigan Long-Term PBB Study.Journal of Exposure Science and Environmental Epidemiology,18,410–420.
Terrell M.L., Berzen A.K., Small C.M., Cameron L.L., Wirth J.J., Marcus M. (2009) A cohort study of the association between secondary sex ratio and parental exposure to polybrominated biphenyl (PBB) and polychlorinated biphenyl (PCB).Environmental Health: A Global Access Science Source,8,Art.No. 35.
The Asahi Shimbun. (2010)Agreement reached to settleMinamata suit. Available at http://www.asahi.com/english/TKY201003300438.html [Last accessed 20 March 2012].
The Australian. (2010)Bonsoy scare triggers calls for iodine oversight, October 04. Available at http://www.theaustralian.com.au/national-affairs/bonsoy-scare-triggers-calls-for-iodine-oversight/story-fn59niix-1225933558885 [Last accessed 20 March 2012].
TIME. (1978)Sabotage: strange fruits, February 13. Available athttp://www.time.com/time/printout/0,8816,915917,00.html[Last accessed 20 March 2012].
Uede K., Furukawa F. (2003) Skin manifestations in acute arsenic poisoning from the Wakayama curry-poisoning incident.British Journal of Dermatology,149, 757–762.
Van Larebeke N., Hens L., Schepens P., Covaci A., Baeyens J., Everaert K., Bernheim J.L., Vlietinck R., De Poorter G.(2001) The Belgian PCB and dioxin incident of January-June 1999: exposure data and potential impact on health.Environmental Health Perspectives,109,265–273.
Vellinga A., Van Loock F. (2002) The dioxin crisis as experiment to determine poultry-related Campylobacter enteritis.Emerging Infectious Diseases,8, 19–22.
Wang Z.G., Feng J.N., Tong Z. (1993) Human toxicosis caused by moldy rice contaminated with fusarium and T-2 toxin.Biomedical and Environmental Sciences: BES,6, 65–70.
Weber J.V., Sharypov V.I. (2009) Ethyl carbamate in foods and beverages: a review.Environmental Chemistry Letters,7,233–247.
World Health Organization. (2010)Initiative to estimate the global burden of foodborne diseases. Available at http://www.who.int/foodsafety/foodborne_disease/ferg/en/index.html [Last accessed 20 March 2012].
William Reed. (2005)New test cuts Sudan risk in food chain. Available at http://www.foodnavigator.com/Science-Nutrition/New-test-cuts-sudan-risk-in-food-chain[Last accessed 20 March 2012].
Yang R., Huang W., Zhang L., Thomas M., Pei X. (2009) Milkadulteration with melamine in China; crisis and response.Quality Assurance and Safety of Crops & Foods,1, 111–116.
Yoshimura T. (2003) Yusho in Japan.Industrial Health,41,139–148.